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Drugs to Watch

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DRUG NAME PHARMA COMPANY PURPOSE STAGE
480848 GlaxoSmithKline Prevent atherosclerosis and heart attack Late-stage trial
Acomplia Sanofi-Synthelabo Combat obesity; reduce risk of heart disease Awaiting regulatory decision
AGI-1067 AtheroGenics Combat artery inflammation Late-stage trial
Alfimeprase Nuvelo Clot-buster Late-stage trial
Celacade Vasogen Treat heart failure Late-stage trial
DG031 DeCode Genetics Combat artery inflammation Mid-stage trial
ETC-216 Pfizer Remove cholesterol from arteries Mid-stage trial
Lipitor-torcetrapib Pfizer Raise good cholesterol Late-stage trial
PPAR alpha agonist Eli Lilly/Ligand Pharmaceuticals Raise good cholesterol, lower triglycerides Mid-stage trial
Rasilez Novartis Reduce high blood pressure Late-stage trial
Thelin Encysive Pharmaceuticals Treat pulmonary hypertension Awaiting regulatory decision
Acapodene GTx Prostate cancer prevention Late-stage trial
AP23573 Ariad Pharmaceuticals Sarcoma Mid-stage trial
Dasatinib Bristol-Myers Squibb Leukemia Awaiting regulatory decision
Ipilumumab Medarex Melanoma Late-stage trial
Panitumumab Amgen Colon cancer, other tumors Awaiting regulatory decision
PTK-787 Novartis/Schering Colon cancer Late-stage trial
Provenge Dendreon Prostate cancer Late-stage trial
Telcyta Telik Ovarian cancer Late-stage trial
Ticilimumab Pfizer Melanoma Mid-stage trial
Tykerb GlaxoSmithKline Breast cancer, bladder cancer Late-stage trial
Arxxant Eli Lilly Treat diabetes complications Late-stage trial
Galida AstraZeneca Lower blood sugar and cholesterol Late-stage trial
Galvus Novartis Control blood sugar Late-stage trial
Januvia Merck Control blood sugar Late-stage trial
NXY-059 Renovis/AstraZeneca Stroke Late-stage trial
Champix Pfizer Smoking addiction Late-stage trial
Flurizan Myriad Genetics Alzheimer's disease Late-stage trial
Gaboxadol Merck Sleeplessness Late-stage trial
Indiplon Neurocrine Biosciences Sleeplessness Late-stage trial
Tysabri Biogen Idec Multiple sclerosis FDA-approved but withdrawn
Zeven Pfizer Treats bacterial infections Awaiting regulatory decision
Denosumab Amgen Treats osteoporosis Mid-stage trial
Lucentis Genentech Treats macular degeneration Mid-stage trial
LymphoStat-B Human Genome Sciences/GlaxoSmithKline Treats lupus, rheumatoid arthritis Mid-stage trial
Maraviroc Pfizer Treats HIV/AIDS Late-stage trial
MYO-029 Wyeth Treats muscular dystrophy Early-stage clinical trial

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